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Article

Mutations of ribosomal protein genes induce overexpression of catalase in Saccharomyces cerevisiae.

FEMS yeast research - 9 Jan 2024

Hsu Ching-Hsiang, Liu Ching-Yu, Lo Kai-Yin

Abstract excerpt

Ribosome assembly defects result in ribosomopathies, primarily caused by inadequate protein synthesis and induced oxidative stress. This study aimed to investigate the link between deleting one ribosomal protein gene (RPG) paralog and oxidative stress response. Our results indicated that RPG mutants exhibited higher oxidant sensitivity than the wild type (WT). The concentrations of H2O2 were increased in the RPG...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38271612
DOI: 10.1093/femsyr/foae005
PMCID: PMC10855018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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