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Article

Frailty and risk of systemic atherosclerosis: A bidirectional Mendelian randomization study.

PloS one - 1 Jan 2024

Xu Liugang, Wang Yajun, Ji Hongyun, Du Wei, You Chunhui, Chen Jin, Jiang Jianyu, Shan Yisi, Pan Qian, Cao Ruihong

Abstract excerpt

BACKGROUND: Numerous observational studies have reported an association between frailty and atherosclerosis. However, the causal relationship between frailty and the occurrence of atherosclerosis in different anatomical sites remains unclear. we conducted a bidirectional Mendelian randomization (MR) study to evaluate the causal relationship between the frailty index (FI), and both systemic atherosclerosis and...

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Identifiers

PMID: 38781179
DOI: 10.1371/journal.pone.0304300
PMCID: PMC11115302

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