Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal associations between frailty and low back pain: a bidirectional two-sample mendelian randomization study.

Aging clinical and experimental research - 11 Sept 2024

Liu Zuying, Fan Jiaming, Bu Huilian, Fu Lijun, Li Cong, Ma Letian, Kong Cunlong, Lu Zhongyuan, Li Xinxin, Wang Jian, Liu Qingying, Yuan Jingjing, Fan Xiaochong

Abstract excerpt

BACKGROUND: Previous observational studies have revealed a potentially robust bidirectional relationship between frailty and low back pain (LBP). However, the precise causal relationship remains unclear. METHODS: To examine the potential causal association between frailty and LBP, we conducted bidirectional two-sample Mendelian randomization analysis (MR) study. Genetic data on frailty index (FI) and LBP were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Causality

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Frailty

Share to Frailty in Older Adults

Share to Genome-Wide Association Study

Share to Low Back Pain

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 39259375
DOI: 10.1007/s40520-024-02843-2
PMCID: PMC11390933

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal associations between frailty and low back pain: a bidirectional two-sample mendelian randomization study.PMID 39259375Read ↗

The causal relationship between risk of developing bronchial asthma and frailty: a bidirectional two-sample Mendelian randomization studySemantic proximity Read ↗

Exploring causality between bone mineral density and frailty: A bidirectional Mendelian randomization study.Semantic proximity Read ↗

Exploring the causal association between frailty index with the common types of arthritis: a Mendelian randomization analysis.Semantic proximity Read ↗

Assessment of the bidirectional causal association between frailty and depression: A Mendelian randomization studySemantic proximity Read ↗

Causal relationship between frailty and chronic obstructive pulmonary disease or asthma: A two sample bidirectional Mendelian randomization studySemantic proximity Read ↗

Bidirectional causal associations between frailty measures and sleep disturbances: a two-sample Mendelian randomization studySemantic proximity Read ↗

Exploring causal correlations between blood inflammatory cytokines and low back pain: a Mendelian randomizationSemantic proximity Read ↗

Frailty and cardiometabolic diseases: a bidirectional Mendelian randomisation study.Semantic proximity Read ↗

The bidirectional association between frailty index and cardiovascular disease: A Mendelian randomization study.Semantic proximity Read ↗

The causal association between asthma and the risk of frailty: A two-sample Mendelian randomization study.Semantic proximity Read ↗

Lipid levels and low back pain risk: A two-sample mendelian randomization study.Semantic proximity Read ↗

Frailty and risk of systemic atherosclerosis: A bidirectional Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.