Article

<i>TP53-</i> mediated clonal hematopoiesis confers increased risk for incident peripheral artery disease

2021-08-23

Abstract excerpt

<h4>Background</h4> Somatic mutations in blood indicative of clonal hematopoiesis of indeterminate potential (CHIP), particularly in DNMT3A , TET2 , and JAK2 , are associated with an increased risk of hematologic malignancy, coronary artery disease, and all-cause mortality. However, whether CHIP is associated with increased risk of peripheral artery disease (PAD) remains unknown. In addition, chemotherapy freq...

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Literature Corpus work: c9da13b3-ff85-5aab-ac13-8472ab322c67
DOI: 10.1101/2021.08.22.21262430

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