Article
[The relationship between the rs6265 polymorphism of the BDNF gene and the level of serum neurotrophic factor in patients with Parkinson's disease].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2024
Nikitina M A, Bragina E Yu, Nazarenko M S, Levchuk L A, Ivanova S A, Boiko A S, Gomboeva D E, Koroleva E S, Alifirova V M
Abstract excerpt
OBJECTIVE: To evaluate the clinical features and the level of serum brain-derived neurotrophic factor (BDNF) in groups of patients with Parkinson's disease (PD) differentiated by the genotypes of BDNF polymorphism (rs6265). MATERIAL AND METHODS: The level of serum BDNF in the biomarkers' multiplex panel of neurodegenerative diseases (HNDG3MAG-36K) was assessed in 134 PD patients. Allele discrimination was carried...
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