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Article

Association of BDNF Val66MET Polymorphism With Parkinson's Disease and Depression and Anxiety Symptoms.

The Journal of neuropsychiatry and clinical neurosciences - 1 Jan 2017

Cagni Fernanda Carvalho, Campêlo Clarissa Loureiro das Chagas, Coimbra Daniel Gomes, Barbosa Mayara Rodrigues, Júnior Luiz Gonzaga Oliveira, Neto Antônio Braz Silva, Ribeiro Alessandra Mussi, Júnior Clécio de Oliveira Godeiro, Gomes de Andrade Tiago, Silva Regina Helena

Abstract excerpt

An association between Parkinson's disease (PD) and brain-derived neurotrophic factor (BDNF) was suggested by several studies, with contradictory results. BDNF is necessary for the survival of dopaminergic neurons in substantia nigra. Val66Met is a common polymorphism of the BDNF gene that affects cognitive and motor processes. The authors studied 104 Brazilian patients with PD and 96 control participants. The...

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Source

Identifiers

PMID: 27852165
DOI: 10.1176/appi.neuropsych.16040062

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of BDNF Val66MET Polymorphism With Parkinson's Disease and Depression and Anxiety Symptoms.PMID 27852165Read ↗

Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with Parkinson's disease in a Greek population.Semantic proximity Read ↗

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Val66Met BDNF polymorphism is associated with Parkinson's disease cognitive impairmentSemantic proximity Read ↗

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No association between brain-derived neurotrophic factor G196A polymorphism and clinical features of Parkinson's disease.Semantic proximity Read ↗

The 712A/G polymorphism of Brain-derived neurotrophic factor is associated with Parkinson's disease but not Major Depressive Disorder in a Chinese Han population.Semantic proximity Read ↗

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Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and its association with select anxiety-related disorders: an updated systematic review and meta-analysis.Semantic proximity Read ↗

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BDNF Val66Met polymorphism is associated with cognitive impairment in Italian patients with Parkinson's disease.Semantic proximity Read ↗

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