Article
Infant lung function and early skin barrier impairment in the development of asthma at age 3 years.
Allergy - 1 Mar 2024
Färdig Martin, Hoyer Angela, Almqvist Catarina, Bains Karen Eline S, Carlsen Karin C Lødrup, Gudmundsdóttir Hrefna Katrín, Granum Berit, Haugen Guttorm Nils, Hedlin Gunilla, Jonassen Christine Monceyron, Konradsen Jon R, Lie Anine, Rehbinder Eva Maria, Skjerven Håvard O, Staff Anne Cathrine, Vettukattil Riyas, Söderhäll Cilla, Nordlund Björn
Abstract excerpt
BACKGROUND: Largely unexplored, we investigated if lower lung function, impaired skin barrier function by transepidermal water loss (TEWL), eczema, and filaggrin (FLG) mutations in infancy were associated with asthma in early childhood. METHODS: From the factorially designed randomized controlled intervention study PreventADALL, we evaluated 1337/2394 children from all randomization groups with information on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.