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Article

Mapping partner drug resistance to guide antimalarial combination therapy policies in sub-Saharan Africa.

Proceedings of the National Academy of Sciences of the United States of America - 20 Jul 2021

Ehrlich Hanna Y, Bei Amy K, Weinberger Daniel M, Warren Joshua L, Parikh Sunil

Abstract excerpt

Resistance to artemisinin-based combination therapies (ACTs) threatens the global control of Plasmodium falciparum malaria. ACTs combine artemisinin-derived compounds with partner drugs to enable multiple mechanisms of clearance. Although ACTs remain widely effective in sub-Saharan Africa, long-standing circulation of parasite alleles associated with reduced partner drug susceptibility may contribute to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34261791
DOI: 10.1073/pnas.2100685118
PMCID: PMC8307356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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