Article
The Role of Host Genetics (and Genomics) in Tuberculosis.
Microbiology spectrum - 1 Oct 2016
Naranbhai Vivek
Abstract excerpt
Familial risk of tuberculosis (TB) has been recognized for centuries. Largely through studies of mono- and dizygotic twin concordance rates, studies of families with Mendelian susceptibility to mycobacterial disease, and candidate gene studies performed in the 20th century, it was recognized that susceptibility to TB disease has a substantial host genetic component. Limitations in candidate gene studies and early...
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