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Article

Genotype imputation accuracy and the quality metrics of the minor ancestry in multi-ancestry reference panels.

Briefings in bioinformatics - 22 Nov 2023

Shi Mingyang, Tanikawa Chizu, Munter Hans Markus, Akiyama Masato, Koyama Satoshi, Tomizuka Kohei, Matsuda Koichi, Lathrop Gregory Mark, Terao Chikashi, Koido Masaru, Kamatani Yoichiro

Abstract excerpt

Large-scale imputation reference panels are currently available and have contributed to efficient genome-wide association studies through genotype imputation. However, whether large-size multi-ancestry or small-size population-specific reference panels are the optimal choices for under-represented populations continues to be debated. We imputed genotypes of East Asian (180k Japanese) subjects using the...

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PMID: 38221906
DOI: 10.1093/bib/bbad509
PMCID: PMC10788679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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