Article

High-depth whole genome sequencing of a large population-specific reference panel: Enhancing sensitivity, accuracy, and imputation

2017-07-24

Abstract excerpt

<h4>Background</h4> While increasingly large reference panels for genome-wide imputation have been recently made available, the degree to which imputation accuracy can be enhanced by population-specific reference panels remains an open question. In the present study, we sequenced at full-depth (≥30x) a moderately large (n=738) cohort of samples drawn from the Ashkenazi Jewish population across two platforms (Illu...

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Literature Corpus work: 2be7d8cc-8068-5a63-a212-40287a20c595
DOI: 10.1101/167924

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