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Article

Oncostatin M stimulates macrophage-polykaryon formation in long-term human bone-marrow cultures.

Cytokine - 1 Feb 1998

Heymann D, Guicheux J, Gouin F, Cottrel M, Daculsi G

Abstract excerpt

Though oncostatin M (OSM) is a potent mediator of the inflammatory reaction, its role in inflammation and bone resorption is still unclear. A long-term bone-marrow culture system is usually developed to allow the formation of multinucleated cells (MNC) and was used here to define the effects of human recombinant OSM on human MNC formation. OSM significantly upregulated (1.9- to 5.6-fold) the number of MNC in...

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Source

Identifiers

PMID: 9512899
DOI: 10.1006/cyto.1997.0258

Genes

OSM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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