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Bone marrow macrophages are involved in the ineffective hematopoiesis of myelodysplastic syndromes

8 Jan 2024

Abstract excerpt

Myelodysplastic syndromes (MDS) are a group of heterogeneous myeloid clonal disorders characterized by ineffective hematopoiesis. Accumulating evidence has shown that macrophages (MΦs) are important components in the regulation of tumor progression and hematopoietic stem cells (HSCs). However, the roles of bone marrow (BM) MΦs in regulating normal and malignant hematopoiesis in different clinical stages of MDS...

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PMID: 38192063
DOI: 10.1002/jcp.31129

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