Article
Genetic Risk Factors for Early-Onset Merkel Cell Carcinoma.
JAMA dermatology - 1 Feb 2024
Mohsin Noreen, Hunt Devin, Yan Jia, Jabbour Austin J, Nghiem Paul, Choi Jaehyuk, Zhang Yue, Freeman Alexandra F, Bergerson Jenna R E, Dell'Orso Stefania, Lachance Kristina, Kulikauskas Rima, Collado Loren, Cao Wenjia, Lack Justin, Similuk Morgan, Seifert Bryce A, Ghosh Rajarshi, Walkiewicz Magdalena A, Brownell Isaac
Abstract excerpt
Importance: Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer. Of the patients who develop MCC annually, only 4% are younger than 50 years. Objective: To identify genetic risk factors for early-onset MCC via genomic sequencing. Design, Setting, and Participants: The study represents a multicenter collaboration between the National Institute of Arthritis and Musculoskeletal and Skin...
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