Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of Family History and Polygenic Risk Score With Longitudinal Prognosis in Parkinson Disease

8 Dec 2023

Abstract excerpt

Background and Objectives: Evidence suggests that either family history or polygenic risk score (PRS) is associated with developing Parkinson disease (PD). However, little is known about the longitudinal prognosis of PD according to family history and higher PRS. Methods: From the Parkinson's Progression Markers Initiative database, 395 patients with PD who followed up for more than 2 years were grouped into...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Neurological disorders and treatments
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38169864
DOI: 10.1212/nxg.0000000000200115

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of Family History and Polygenic Risk Score With Longitudinal Prognosis in Parkinson DiseasePMID 38169864Read ↗

Association of Polygenic Risk Score With Cognitive Decline and Motor Progression in Parkinson Disease.Semantic proximity Read ↗

Polygenic Risk Scores Contribute to Personalized Medicine of Parkinson’s DiseaseSemantic proximity Read ↗

A cumulative genetic risk score predicts progression in Parkinson's disease.Semantic proximity Read ↗

Polygenic risk score-based prediction for Parkinson’s diseaseSemantic proximity Read ↗

Family History in Parkinson's Disease: A National Cross-Sectional Study.Semantic proximity Read ↗

Progression to Parkinson's dementia is not modulated by genetic risk variants for Alzheimer's or Parkinson's disease.Semantic proximity Read ↗

Genome-Wide Polygenic Risk Score Identifies Individuals at Elevated Parkinson’s Disease RiskSemantic proximity Read ↗

Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels.Semantic proximity Read ↗

Parkinson's disease and family history.Semantic proximity Read ↗

Risk prediction for complex diseases: application to Parkinson disease.Semantic proximity Read ↗

Assessing the role of polygenic background on the penetrance of monogenic forms in Parkinson’s diseaseSemantic proximity Read ↗

An improved polygenic score for Parkinson’s disease partly explains variable penetrance of genetic Parkinson’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.