Article
Social Threat-Safety Test Uncovers Psychosocial Stress-Related Phenotypes.
Journal of visualized experiments : JoVE - 15 Dec 2023
Ayash Sarah, Müller Marianne, Schmitt Ulrich
Abstract excerpt
Social stress is a major cause of the development of mental disorders. To enhance the translational value of preclinical studies, social stress experience and its behavioral impact on mice should be comparable to humans. Chronic social defeat (CSD) utilizes a type of social stress involving physical attacks and sensory threats to induce mental dysfunctions resembling human affective disorders. To strengthen the...
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