Article
Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain.
Neuroscience - 29 Sept 2011
Savignac H M, Finger B C, Pizzo R C, O'Leary O F, Dinan T G, Cryan J F
Abstract excerpt
Stress and genetic predisposition are two of the major risk factors for a variety of psychiatric illnesses. Inbred mouse strains are considered useful tools in dissecting the genetic basis of complex disorders. Indeed, mice of the C57BL/6 and BALB/c strains, differing markedly in anxiety behaviours, are among the most widely used in psychopharmacological research. However, there is a paucity of studies...
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