Article
Social defeat stress induces a depression-like phenotype in adolescent male c57BL/6 mice.
Stress (Amsterdam, Netherlands) - 1 May 2014
Iñiguez Sergio D, Riggs Lace M, Nieto Steven J, Dayrit Genesis, Zamora Norma N, Shawhan Kristi L, Cruz Bryan, Warren Brandon L
Abstract excerpt
Abstract Exposure to stress is highly correlated with the emergence of mood-related illnesses. Because major depressive disorder often emerges in adolescence, we assessed the effects of social defeat stress on responses to depressive-like behaviors in juvenile mice. To do this, postnatal day (PD) 35 male c57BL/6 mice were exposed to 10 days of social defeat stress (PD35-44), while control mice were handled daily....
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