Hereditary spastic paraplegia: Novel insights into the pathogenesis and management

Abstract excerpt

Hereditary spastic paraplegia is a genetically heterogeneous neurodegenerative disorder characterised primarily by muscle stiffness in the lower limbs. Neurodegenerative disorders are conditions that result from cellular and metabolic abnormalities, many of which have strong genetic ties. While ageing is a known contributor to these changes, certain neurodegenerative disorders can manifest early in life,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hereditary Neurological Disorders
• Share to Neurogenetic and Muscular Disorders Research
• Share to Neurological diseases and metabolism