Article
Clinical features and management of hereditary spastic paraplegia.
Arquivos de neuro-psiquiatria - 1 Mar 2014
Faber Ingrid, Servelhere Katiane R, Martinez Alberto R M, D'Abreu Anelyssa, Lopes-Cendes Iscia, França Marcondes C
Abstract excerpt
Hereditary spastic paraplegia (HSP) is a group of genetically-determined disorders characterized by progressive spasticity and weakness of lower limbs. An apparently sporadic case of adult-onset spastic paraplegia is a frequent clinical problem and a significant proportion of cases are likely to be of genetic origin. HSP is clinically divided into pure and complicated forms. The later present with a wide range of...
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