Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hereditary spastic paraplegias proteome: common pathways and pathogenetic mechanisms.

Expert review of proteomics - 1 Jan 2000

Martinello Chiara, Panza Emanuele, Orlacchio Antonio

Abstract excerpt

INTRODUCTION: Hereditary spastic paraplegias (HSPs) are a group of inherited neurodegenerative disorders characterized by progressive spasticity and weakness of the lower limbs. These conditions are caused by lesions in the neuronal pyramidal tract and exhibit clinical and genetic variability. Ongoing research focuses on understanding the underlying mechanisms of HSP onset, which ultimately lead to neuronal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Botulinum Toxin and Related Neurological Disorders
Share to Hereditary Neurological Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Neurological diseases and metabolism

Share to Phenotype

Share to Proteome

Share to Quality of Life

Share to Spastic Paraplegia, Hereditary

Source

Identifiers

PMID: 37788157
DOI: 10.1080/14789450.2023.2260952

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hereditary spastic paraplegias proteome: common pathways and pathogenetic mechanisms.PMID 37788157Read ↗

Delving into the complexity of hereditary spastic paraplegias: how unexpected phenotypes and inheritance modes are revolutionizing their nosologySemantic proximity Read ↗

Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms.Semantic proximity Read ↗

Hereditary spastic paraplegia: clinical-genetic characteristics and evolving molecular mechanisms.Semantic proximity Read ↗

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms.Semantic proximity Read ↗

Hereditary spastic paraplegia.Semantic proximity Read ↗

Converging cellular themes for the hereditary spastic paraplegias.Semantic proximity Read ↗

Hereditary spastic paraplegia: Novel insights into the pathogenesis and managementSemantic proximity Read ↗

Insights into Clinical, Genetic, and Pathological Aspects of Hereditary Spastic Paraplegias: A Comprehensive OverviewSemantic proximity Read ↗

Hereditary spastic paraplegia: Genetic heterogeneity and common pathways.Semantic proximity Read ↗

Lysosome Function and Dysfunction in Hereditary Spastic ParaplegiasSemantic proximity Read ↗

Hereditary Spastic Paraplegia: From Genes, Cells and Networks to Novel Pathways for Drug DiscoverySemantic proximity Read ↗

Investigating the molecular mechanisms of Hereditary Spastic Paraplegia neuropathiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.