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Article

B cell phylogenetics in the single cell era.

Trends in immunology - 1 Jan 2024

Hoehn Kenneth B, Kleinstein Steven H

Abstract excerpt

The widespread availability of single-cell RNA sequencing (scRNA-seq) has led to the development of new methods for understanding immune responses. Single-cell transcriptome data can now be paired with B cell receptor (BCR) sequences. However, RNA from BCRs cannot be analyzed like most other genes because BCRs are genetically diverse within individuals. In humans, BCRs are shaped through recombination followed by...

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Identifiers

PMID: 38151443
DOI: 10.1016/j.it.2023.11.004
PMCID: PMC10872299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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