Article
Genetic Characterization of Pediatric Mixed Phenotype Acute Leukemia (MPAL).
Cancer genomics & proteomics - 1 Jan 2000
Panagopoulos Ioannis, Andersen Kristin, Johannsdottir Inga Maria Rinvoll, Tandsæther Maren Randi, Micci Francesca, Heim Sverre
Abstract excerpt
BACKGROUND/AIM: Mixed phenotype acute leukemia (MPAL) is a rare hematologic malignancy in which the leukemic cells cannot be assigned to any specific lineage. The lack of well-defined, pathogenetically relevant diagnostic criteria makes the clinical handling of MPAL patients challenging. We herein report the genetic findings in bone marrow cells from two pediatric MPAL patients. PATIENTS AND METHODS: Bone marrow...
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