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Cellular atlas of the human ovary using morphologically guided spatial transcriptomics and single-cell sequencing

5 Apr 2024

Abstract excerpt

The reproductive and endocrine functions of the ovary involve spatially defined interactions among specialized cell populations. Despite the ovary's importance in fertility and endocrine health, functional attributes of ovarian cells are largely uncharacterized. Here, we profiled >18,000 genes in 257 regions from the ovaries of two premenopausal donors to examine the functional units in the ovary. We also...

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PMID: 38578993
DOI: 10.1126/sciadv.adm7506

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