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Development of a molecular barcode detection system for pancreaticobiliary malignancies and comparison with next-generation sequencing.

Cancer genetics - 1 Jan 2024

Ohyama Hiroshi, Hirotsu Yosuke, Amemiya Kenji, Mikata Rintaro, Amano Hiroyuki, Hirose Sumio, Oyama Toshio, Iimuro Yuji, Kojima Yuichiro, Mochizuki Hitoshi, Kato Naoya, Omata Masao

Abstract excerpt

BACKGROUND: Obtaining sufficient tumor tissue for genomic profiling is challenging in pancreaticobiliary cancer (PBCA). We determined the utility of molecular barcoding (MB) of liquid biopsies (bile, duodenal fluid, and plasma) for highly sensitive genomic diagnosis and detection of druggable mutations for PBCA. METHODS: Two in-house panels of 60 genes (non-MB panel) and 21 genes using MB (MB panel) were used for...

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PMID: 38113555
DOI: 10.1016/j.cancergen.2023.12.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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