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Article

Detection of actionable mutations in archived cytological bile specimens.

Journal of hepato-biliary-pancreatic sciences - 1 Oct 2021

Ohyama Hiroshi, Hirotsu Yosuke, Amemiya Kenji, Oyama Toshio, Iimuro Yuji, Kojima Yuichiro, Mikata Rintaro, Mochizuki Hitoshi, Kato Naoya, Omata Masao

Abstract excerpt

BACKGROUND/PURPOSE: There are limitations in obtaining sufficient pancreaticobiliary tumor tissue for genomic profiling of tumors. Herein, we investigated whether archived cytological specimen (ACS) is suitable for genomic profiling to identify oncogenic and drug-matched mutations. METHODS: We constructed a pancreaticobiliary cancer panel for targeted sequencing covering 60 significantly mutated genes...

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PMID: 34022115
DOI: 10.1002/jhbp.994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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