Article
Current status of molecular diagnostic approaches using liquid biopsy.
Journal of gastroenterology - 1 Sept 2023
Takahashi Kenji, Takeda Yohei, Ono Yusuke, Isomoto Hajime, Mizukami Yusuke
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal cancers, and developing an efficient and reliable approach for its early-stage diagnosis is urgently needed. Precancerous lesions of PDAC, such as pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasms (IPMN), arise through multiple steps of driver gene alterations in KRAS, TP53, CDKN2A, SMAD4, or...
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