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Article

Usefulness of multigene liquid biopsy of bile for identifying driver genes of biliary duct cancers.

Cancer science - 1 Dec 2024

Ito Shin, Ando Mika, Aoki Shuichi, Soma Satoshi, Zhang Jie, Hirano Naohiro, Kashiwagi Ryosuke, Murakami Keigo, Yoshimachi Shingo, Sato Hideaki, Kusaka Akiko, Iseki Masahiro, Inoue Koetsu, Mizuma Masamichi, Kume Kiyoshi, Nakagawa Kei, Masamune Atsushi, Asano Naoki, Yasuda Jun, Unno Michiaki

Abstract excerpt

Liquid biopsy (LB) is an essential tool for obtaining tumor-derived materials with minimum invasion. Bile has been shown to contain much higher free nucleic acid levels than blood plasma and can be collected through endoscopic procedures. Therefore, bile possesses high potential as a source of tumor derived cell-free DNA (cfDNA) for bile duct cancers. In this study, we show that a multigene panel for plasma LB...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39377143
DOI: 10.1111/cas.16365
PMCID: PMC11611759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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