Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analyses identify brain imaging-derived phenotypes associated with the risk of amyotrophic lateral sclerosis.

Cerebral cortex (New York, N.Y. : 1991) - 14 Jan 2024

Wang Yinan, Shen Ouxi, Xu Qingyun, Sun Lulu, Jia Yiming, Liu Yi, He Yu, Chang Xinyue, Guo Daoxia, Shi Mengyao, Chen Guo-Chong, Zheng Jin, Zhu Zhengbao

Abstract excerpt

Brain imaging-derived phenotypes have been suggested to be associated with amyotrophic lateral sclerosis in observational studies, but whether these associations are causal remains unclear. We aimed to assess the potential bidirectional causal associations between imaging-derived phenotypes and amyotrophic lateral sclerosis using bidirectional 2-sample Mendelian randomization analyses. Summary statistics for 469...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Neuroimaging

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 38112636
DOI: 10.1093/cercor/bhad496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analyses identify brain imaging-derived phenotypes associated with the risk of amyotrophic lateral sclerosis.PMID 38112636Read ↗

Causal Associations Between Imaging-derived Phenotypes and Risk of Alzheimer’s Disease and Other Neurodegenerative Disorders: A Mendelian Randomization StudySemantic proximity Read ↗

Causal Associations Between Imaging-derived Phenotypes and Risk of Alzheimer’s Disease and Other Neurodegenerative Disorders: A Mendelian Randomization StudySemantic proximity Read ↗

Bidirectional two-sample Mendelian randomization analyses support causal relationships between structural and diffusion imaging-derived phenotypes and the risk of major neurodegenerative diseases.Semantic proximity Read ↗

A review of Mendelian randomization in amyotrophic lateral sclerosisSemantic proximity Read ↗

Mendelian randomization analysis implicates bidirectional associations between brain imaging-derived phenotypes and ischemic stroke.Semantic proximity Read ↗

Mendelian randomization and clinical retrospective radiomics study reveal causal relationships between brain imaging-derived phenotypes and epilepsy risk.Semantic proximity Read ↗

Causal relationship between imaging-derived phenotypes and neurodegenerative diseases: a Mendelian randomization study.Semantic proximity Read ↗

Understanding Causal Relationships between Imaging-Derived Phenotypes and Parkinson’s Disease: A Mendelian Randomization and Observational StudySemantic proximity Read ↗

Identification of potential drug targets for amyotrophic lateral sclerosis by Mendelian randomization analysis based on brain and plasma proteomics.Semantic proximity Read ↗

Assessment of bidirectional relationships between brain imaging-derived phenotypes and stroke: a Mendelian randomization study.Semantic proximity Read ↗

Association between type 2 diabetes and amyotrophic lateral sclerosisSemantic proximity Read ↗

Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.