Article
Mendelian randomization analysis implicates bidirectional associations between brain imaging-derived phenotypes and ischemic stroke.
Cerebral cortex (New York, N.Y. : 1991) - 14 Oct 2023
Jia Yiming, Sun Hongyan, Sun Lulu, Wang Yinan, Xu Qingyun, Liu Yi, Chang Xinyue, He Yu, Guo Daoxia, Shi Mengyao, Chen Guo-Chong, Zheng Jin, Zhang Yonghong, Zhu Zhengbao
Abstract excerpt
Brian imaging-derived phenotypes (IDPs) have been suggested to be associated with ischemic stroke, but the causality between them remains unclear. In this bidirectional two-sample Mendelian randomization (MR) study, we explored the potential causal relationship between 461 imaging-derived phenotypes (n = 33,224, UK Biobank) and ischemic stroke (n = 34,217 cases/406,111 controls, Multiancestry Genome-Wide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.