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Association between type 2 diabetes and amyotrophic lateral sclerosis

15 Feb 2022

Abstract excerpt

Type 2 diabetes (T2D) and amyotrophic lateral sclerosis (ALS) are associated consistently. However, it is currently unknown whether this association is causal. We aimed to estimate the unconfounded, causal association between T2D on ALS using a two-sample Mendelian randomization approach both in European and East Asian ancestry. Genetic variants strongly associated with T2D and each T2D markers were used to...

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PMID: 35169211
DOI: 10.1038/s41598-022-06463-6

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