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Article

Complex interplay between FMRP and DHX9 during DNA replication stress.

The Journal of biological chemistry - 1 Jan 2024

Chakraborty Arijita, Dutta Arijit, Dettori Leonardo G, Daoud Rosemarie, Li Jing, Gonzalez Leticia, Xue Xiaoyu, Hehnly Heidi, Sung Patrick, Bah Alaji, Feng Wenyi

Abstract excerpt

Mutations in, or deficiency of, fragile X messenger ribonucleoprotein (FMRP) is responsible for the Fragile X syndrome (FXS), the most common cause for inherited intellectual disability. FMRP is a nucleocytoplasmic protein, primarily characterized as a translation repressor with poorly understood nuclear function(s). We recently reported that FXS patient cells lacking FMRP sustain higher level of DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38110032
DOI: 10.1016/j.jbc.2023.105572
PMCID: PMC10825048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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