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Article

Cancer metabolism as a central driving force of glioma pathogenesis.

Brain tumor pathology - 1 Jul 2016

Masui Kenta, Cavenee Webster K, Mischel Paul S

Abstract excerpt

The recent identification of distinct genetic and epigenetic features in each glioma entity is leading to a multilayered, integrated diagnostic approach combining histologic features with molecular genetic information. Somatic mutations in isocitrate dehydrogenase (IDH) and receptor tyrosine kinase (RTK) pathways are key oncogenic events in diffuse gliomas, including lower grade (grade II and III) gliomas (LGG)...

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Source

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Identifiers

PMID: 27295313
DOI: 10.1007/s10014-016-0265-5
PMCID: PMC5488809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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