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Glioblastomas: Hijacking Metabolism to Build a Flexible Shield for Therapy Resistance

22 Feb 2023

Abstract excerpt

Significance: Glioblastomas (GBMs) are among the most lethal tumors despite the almost exclusive localization to the brain. This is largely due to therapeutic resistance. Radiation and chemotherapy significantly increase the survival for GBM patients, however, GBMs always recur, and the median overall survival is just over a year. Proposed reasons for such intractable resistance to therapy are numerous and...

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Identifiers

PMID: 37022791
DOI: 10.1089/ars.2022.0088

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