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Article

mTORC2 in the center of cancer metabolic reprogramming.

Trends in endocrinology and metabolism: TEM - 1 Jul 2014

Masui Kenta, Cavenee Webster K, Mischel Paul S

Abstract excerpt

Metabolic reprogramming is a central hallmark of cancer, enabling tumor cells to obtain the macromolecular precursors and energy needed for rapid tumor growth. Understanding how oncogenes coordinate altered signaling with metabolic reprogramming and global transcription may yield new insights into tumor pathogenesis, and provide a new landscape of promising drug targets, while yielding important clues into...

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Identifiers

PMID: 24856037
DOI: 10.1016/j.tem.2014.04.002
PMCID: PMC4077930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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