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The involvement of E3 ubiquitin ligases in the development and progression of colorectal cancer

16 Dec 2023

Abstract excerpt

To date, colorectal cancer (CRC) still has limited therapeutic efficacy and poor prognosis and there is an urgent need for novel targets to improve the outcome of CRC patients. The highly conserved ubiquitination modification mediated by E3 ubiquitin ligases is an important mechanism to regulate the expression and function of tumor promoters or suppressors in CRC. In this review, we provide an overview of E3...

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PMID: 38104139
DOI: 10.1038/s41420-023-01760-z

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