Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unraveling the Potential Role of NEDD4-like E3 Ligases in Cancer

16 Oct 2022

Abstract excerpt

Cancer is a deadly disease worldwide, with an anticipated 19.3 million new cases and 10.0 million deaths occurring in 2020 according to GLOBOCAN 2020. It is well established that carcinogenesis and cancer development are strongly linked to genetic changes and post-translational modifications (PTMs). An important PTM process, ubiquitination, regulates every aspect of cellular activity, and the crucial enzymes in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Peptidase Inhibition and Analysis
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36293239
DOI: 10.3390/ijms232012380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unraveling the Potential Role of NEDD4-like E3 Ligases in CancerPMID 36293239Read ↗

Expression and regulatory network of E3 ubiquitin ligase NEDD4 family in cancersSemantic proximity Read ↗

NEDD4 E3 ubiquitin ligases: Promising biomarkers and therapeutic targets for cancerSemantic proximity Read ↗

NEDD4 E3 ligase: Functions and mechanism in human cancerSemantic proximity Read ↗

The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectivesSemantic proximity Read ↗

The Next Frontier: Translational Development of Ubiquitination, SUMOylation, and NEDDylation in CancerSemantic proximity Read ↗

Downregulation of NEDD4L by EGFR Signaling Promotes the Development of Lung AdenocarcinomaSemantic proximity Read ↗

The regulatory roles of the E3 ubiquitin ligase NEDD4 family in DNA damage responseSemantic proximity Read ↗

NEDD4L-Induced Ubiquitination Mediated UBE2T Degradation Inhibits Progression of Lung Adenocarcinoma Via PI3K-AKT SignalingSemantic proximity Read ↗

The involvement of E3 ubiquitin ligases in the development and progression of colorectal cancerSemantic proximity Read ↗

Cullin-RING Ligase 4 in Cancer: Structure, Functions, and MechanismsSemantic proximity Read ↗

The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implicationsSemantic proximity Read ↗

The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.