Article
The atrial and ventricular myocardial proteome of end-stage lamin heart disease.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology - 1 Jan 2023
Topriceanu Constantin-Cristian, Alfarih Mashael, Hughes Alun D, Shiwani Hunain, Chan Fiona, Mohiddin Saidi A, Moody William, Steeds Richard P, O'Brien Benjamin, Vowinckel Jakob, Syrris Petros, Coats Caroline, Pettit Stephen, Arbustini Eloisa, Moon James C, Captur Gabriella
Abstract excerpt
Lamins A/C (encoded by LMNA gene) can lead to dilated cardiomyopathy (DCM). This pilot study sought to explore the postgenomic phenotype of end-stage lamin heart disease. Consecutive patients with end-stage lamin heart disease (LMNA-group, n = 7) and ischaemic DCM (ICM-group, n = 7) undergoing heart transplantation were prospectively enrolled. Samples were obtained from left atrium (LA), left ventricle (LV),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.