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Article

Pleiotropic genetic association analysis with multiple phenotypes using multivariate response best-subset selection.

BMC genomics - 11 Dec 2023

Guo Hongping, Li Tong, Wang Zixuan

Abstract excerpt

Genetic pleiotropy refers to the simultaneous association of a gene with multiple phenotypes. It is widely distributed in the whole genome and can help to understand the common genetic mechanism of diseases or traits. In this study, a multivariate response best-subset selection (MRBSS) model based pleiotropic association analysis method is proposed. Different from the traditional genetic association model, the...

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Identifiers

PMID: 38082214
DOI: 10.1186/s12864-023-09820-5
PMCID: PMC10712198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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