Article
Predicting disease trait with genomic data: a composite kernel approach.
Briefings in bioinformatics - 1 Jul 2017
Yang Haitao, Li Shaoyu, Cao Hongyan, Zhang Chichen, Cui Yuehua
Abstract excerpt
With the advancement of biotechniques, a vast amount of genomic data is generated with no limit. Predicting a disease trait based on these data offers a cost-effective and time-efficient way for early disease screening. Here we proposed a composite kernel partial least squares (CKPLS) regression model for quantitative disease trait prediction focusing on genomic data. It can efficiently capture nonlinear...
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