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Article

Whole-exome and transcriptome sequencing of refractory diffuse large B-cell lymphoma.

Oncotarget - 27 Dec 2016

Park Ha Young, Lee Seung-Bok, Yoo Hae-Yong, Kim Seok-Jin, Kim Won-Seog, Kim Jong-Il, Ko Young-Hyeh

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. Although rituximab therapy improves clinical outcome, some patients develop resistant DLBCL; however, the genetic alterations in these patients are not well documented. To identify the genetic background of refractory DLBCL, we conducted whole-exome sequencing and transcriptome sequencing for six patients with refractory and...

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Topics

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Share to DNA Copy Number Variations
Share to Exome
Share to Gene Fusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to REL gene

Share to Genes, p53

Share to Lymphoma, Large B-Cell, Diffuse

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Source

Open in PubMed Open full text

Identifiers

PMID: 27835906
DOI: 10.18632/oncotarget.13239
PMCID: PMC5349924

Genes

AHR
CUX1
DHX16
FANCL
FNBP4
MYD88
MYO6
NMT1
PRDM15
PRKCB
REL
SORCS3
TRRAP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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