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Article

Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2016

Morin Ryan D, Assouline Sarit, Alcaide Miguel, Mohajeri Arezoo, Johnston Rebecca L, Chong Lauren, Grewal Jasleen, Yu Stephen, Fornika Daniel, Bushell Kevin, Nielsen Torsten Holm, Petrogiannis-Haliotis Tina, Crump Michael, Tosikyan Axel, Grande Bruno M, MacDonald David, Rousseau Caroline, Bayat Maryam, Sesques Pierre, Froment Remi, Albuquerque Marco, Monczak Yury, Oros Kathleen Klein, Greenwood Celia, Riazalhosseini Yasser, Arseneault Madeleine, Camlioglu Errol, Constantin André, Pan-Hammarstrom Qiang, Peng Roujun, Mann Koren K, Johnson Nathalie A

Abstract excerpt

PURPOSE: Relapsed or refractory diffuse large B-cell lymphoma (rrDLBCL) is fatal in 90% of patients, and yet little is known about its biology. EXPERIMENTAL DESIGN: Using exome sequencing, we characterized the mutation profiles of 38 rrDLBCL biopsies obtained at the time of progression after immunochemotherapy. To identify genes that may be associated with relapse, we compared the mutation frequency in samples...

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PMID: 26647218
DOI: 10.1158/1078-0432.CCR-15-2123

Genes

STAT6
NFKBIZ
CCND3
FOXO1
MYD88
NFKBIE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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