Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sicilian semi- and supercentenarians: age-related Tγδ cell immunophenotype contributes to longevity trait definition.

Clinical and experimental immunology - 12 Mar 2024

Ligotti Mattia Emanuela, Accardi Giulia, Aiello Anna, Calabrò Anna, Caruso Calogero, Corsale Anna Maria, Dieli Francesco, Di Simone Marta, Meraviglia Serena, Candore Giuseppina

Abstract excerpt

The immune system of semi- (from ≥105 to <110 years old) and supercentenarians (≥110 years old), i.e. oldest centenarians, is thought to have characteristics that allow them to reach extreme longevity in relatively healthy status. Thus, we investigated variations of the two principal subsets of Tγδ, Vδ1, and Vδ2, and their functional subsets using the markers defining Tαβ cells, i.e. CD27, CD45RA, in a cohort of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Longevity

Share to Phenotype

Share to Receptors, Antigen, T-Cell, gamma-delta

Share to T-Lymphocyte Subsets

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 38066662
DOI: 10.1093/cei/uxad132
PMCID: PMC10929699

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sicilian semi- and supercentenarians: age-related Tγδ cell immunophenotype contributes to longevity trait definition.PMID 38066662Read ↗

Association among Terminally Differentiated T Cells, Frailty, and Dependency in a Group of Cuban CentenariansSemantic proximity Read ↗

Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevitySemantic proximity Read ↗

Immunological features beyond CD4/CD8 ratio values in older individuals.Semantic proximity Read ↗

Immune-Inflammatory Response in Lifespan—What Role Does It Play in Extreme Longevity? A Sicilian Semi- and Supercentenarians StudySemantic proximity Read ↗

The Phenotypic Characterization of the Oldest Italian Man from December 28, 2020, to September 23, 2021, A.T., Strengthens the Idea That the Immune System can Play a Key Role in the Attainment of Extreme LongevitySemantic proximity Read ↗

Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenariansSemantic proximity Read ↗

Single-cell transcriptomics reveals expansion of cytotoxic CD4 T-cells in supercentenariansSemantic proximity Read ↗

Immune-Inflammatory Response in Lifespan. What Role Does It Play in Extreme Longevity? A Sicilian Semi- and Supercentenarians StudySemantic proximity Read ↗

Impact of age, sex and CMV-infection on peripheral T cell phenotypes: results from the Berlin BASE-II Study.Semantic proximity Read ↗

Markers of immunosenescence in CMV seropositive healthy elderly adultsSemantic proximity Read ↗

The Phenotypic Characterization of the Oldest Italian Men from December 28, 2020 to September 23, 2021, Antonino Turturici, Suggests a Role for Immune System in the Attainment of Extreme LongevitySemantic proximity Read ↗

Aging-Related Immune Cell Phenotypes and Mortality in the Framingham Heart StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.