Article
Impact of age, sex and CMV-infection on peripheral T cell phenotypes: results from the Berlin BASE-II Study.
Biogerontology - 1 Oct 2015
Di Benedetto Svetlana, Derhovanessian Evelyna, Steinhagen-Thiessen Elisabeth, Goldeck David, Müller Ludmila, Pawelec Graham
Abstract excerpt
Advancing age is characterized by functional and phenotypic alterations in the distribution of circulating T-cell subsets, some of which are exacerbated by a latent infection with the persistent herpesvirus, cytomegalovirus (CMV). The influence of age, sex and CMV-infection on T-cell subpopulations in the peripheral blood remains incompletely understood. Here, T cells from 157 participants of the Berlin Aging...
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