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Article

Immunological features beyond CD4/CD8 ratio values in older individuals.

Aging - 26 May 2021

Garrido-Rodríguez Vanesa, Herrero-Fernández Inés, Castro María José, Castillo Ana, Rosado-Sánchez Isaac, Galvá María Isabel, Ramos Raquel, Olivas-Martínez Israel, Bulnes-Ramos Ángel, Cañizares Julio, Leal Manuel, Pacheco Yolanda María

Abstract excerpt

The CD4/CD8 T-cell ratio is emerging as a relevant marker of evolution for many pathologies and therapies. We aimed to explore immunological features beyond CD4/CD8 ratio values in older subjects (>65 years old) who were classified as having lower (<1.4), intermediate (1.4-2), or higher (>2) ratio values. The lower group showed a lower thymic output (sj/β-TREC ratio) and frequency of naïve T-cells, concomitant...

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Identifiers

PMID: 34038386
DOI: 10.18632/aging.203109
PMCID: PMC8202849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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