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Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenarians

28 Nov 2018

Abstract excerpt

It is generally recognized that the function of the immune system declines with increased age and one of the major immune changes is impaired T-cell responses upon antigen presentation/stimulation. Some "high-performing" centenarians (100+ years old) are remarkably successful in escaping, or largely postponing, major age-related diseases. However, the majority of centenarians ("low-performing") have experienced...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 30488553
DOI: 10.1111/acel.12859

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