Evaluation of bidirectional relationships between risk preference and mood disorders: A 2-sample Mendelian randomization study.

Abstract excerpt

BACKGROUND: Risk preference is often defined as the tendency to engage in risky activities. Increasing evidence shows that risk preference is associated with mood disorders. However, the causality and direction of this association are not clear. METHODS: Genome-wide association study summary data of risk preference in 939,908 participants from UK Biobank and 23andMe were used to identify general risk preference....

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