Article
Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression.
Translational psychiatry - 4 Sept 2018
Strawbridge Rona J, Ward Joey, Lyall Laura M, Tunbridge Elizabeth M, Cullen Breda, Graham Nicholas, Ferguson Amy, Johnston Keira J A, Lyall Donald M, Mackay Daniel, Cavanagh Jonathan, Howard David M, Adams Mark J, Deary Ian, Escott-Price Valentina, O'Donovan Michael, McIntosh Andrew M, Bailey Mark E S, Pell Jill P, Harrison Paul J, Smith Daniel J
Abstract excerpt
Risk-taking behaviour is an important component of several psychiatric disorders, including attention-deficit hyperactivity disorder, schizophrenia and bipolar disorder. Previously, two genetic loci have been associated with self-reported risk taking and significant genetic overlap with psychiatric disorders was identified within a subsample of UK Biobank. Using the white British participants of the full UK...
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