Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort.

doi:10.1038/s41398-017-0079-1

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Article

Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort.

Translational psychiatry - 2 Feb 2018

Strawbridge Rona J, Ward Joey, Cullen Breda, Tunbridge Elizabeth M, Hartz Sarah, Bierut Laura, Horton Amy, Bailey Mark E S, Graham Nicholas, Ferguson Amy, Lyall Donald M, Mackay Daniel, Pidgeon Laura M, Cavanagh Jonathan, Pell Jill P, O'Donovan Michael, Escott-Price Valentina, Harrison Paul J, Smith Daniel J

Abstract excerpt

Risk-taking behaviour is a key component of several psychiatric disorders and could influence lifestyle choices such as smoking, alcohol use, and diet. As a phenotype, risk-taking behaviour therefore fits within a Research Domain Criteria (RDoC) approach, whereby identifying genetic determinants of this trait has the potential to improve our understanding across different psychiatric disorders. Here we report a...

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Identifiers

PMID: 29391395
DOI: 10.1038/s41398-017-0079-1
PMCID: PMC5804026

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CADM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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