Major depression disorder may causally associate with the increased atrial fibrillation risk: evidence from two-sample mendelian randomization analyses

Abstract excerpt

BACKGROUND: Observational studies have revealed a link between major depressive disorder (MDD) and a higher chance of developing atrial fibrillation (AF). It is still uncertain whether or not this correlation indicates a causal relationship. This research set out to evaluate the causal impact of MDD on AF. METHODS: To evaluate the causal relationship between MDD and AF, we employed a two-sample Mendelian...

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